Journal papers

A. Acevedo, S. Alférez, A. Merino, L. Puigví, J. Rodellar. Recognition of peripheral blood cell images using convolutional neural networks. Computer Methods and Programs in Biomedicine 2019. doi.org/10.1016/j.cmpb.2019.105020105020.

 

L. Boldú, A. Merino, S. Alférez, A. Molina, A. Acevedo, J. Rodellar. Automatic recognition of different types of acute leukaemia in peripheral blood by image analysis. J CLin Pathol. 2019;0:1-7.doi:10.1136/jclinpath-2019-205949.

 

S. Alférez, A. Merino, A. Acevedo, L. Puigví, J. Rodellar. Colour clustering segmentation framework for image analysis of malignant lymphoid cells in peripheral blood. Med Biol Eng Comput. 2019;57(6):1265-1283. https://doi.org/10.1007/s11517-019-01954-7.

 

L. Puigví, S. Alférez, L. Boldú, A. Acevedo, J. Rodellar, A. Merino. Quantitative cytological descriptors to differentiate CLL, Sézary, Granular and Villous lymphocytes through image analysis. Am J Clin Pathol. 2018;152(1):74-85. doi:10.1093/ajcp/aqz025.

 

J. Rodellar, S. Alférez, A. Acevedo, A. Molina, A. Merino. Image processing and machine learning in the morphological analysis of blood cells. Int Lab Hem. 2018;40(Suppl 1):46-53.

 

A. Merino, L. Puigví, L. Boldú, S. Alférez, J. Rodellar. Optimizing morphology through blood cell image analysis. Int Lab Hem. 2018;40(Suppl 1):54-61. doi:10.1111/ijlh.12832.

 

A. Merino, L. Boldú, A. Ermens. Acute myeloid leukaemia: How to combine multiple tools. Int Lab Hem. 2018;40(Suppl 1):109-119. doi:10.1111/ijlh.12831.

 

L. Puigví, A. Merino, S. Alférez, A. Acevedo, J. Rodellar. New quantitative features for the morphological differentiation of abnormal lymphoid cell images from peripheral blood. J Clin Pathol. 2017;0:1-11. doi:10.1136/jclinpath-2017-204389.

 

L. Bigorra, A. Merino, S. Alférez, J. Rodellar. Feature analysis and automatic identification of leukemic lineage blast cells and reactive lymphoid cells from peripheral blood cell images. J Clin Lab Anal. 2016 Jul 18. doi: 10.1002/jcla.22024.

 

S. Alférez, A. Merino, L. Bigorra, J. Rodellar. Characterization and automatic screening of reactive and abnormal neoplastic B lymphoid cells from peripheral blood. Int J Lab Hematol. 2016 Apr;38(2):209-19. doi: 10.1111/ijlh.12473

 

T.B. Keng, B. De La Salle, G. Bourner, A. Merino, J.Y. Han, Y. Kawai, M.T. Peng, R. McCafferty, on behalf of the International Council for Standardization in Haematology (ICSH). Standardisation of Haematology Critical Results Management in Adults: An international Council for Standardisation in Haematology, ICSH, survey and recommendations. Int J Lab Hematol. 2016 Oct;38(5):457-71. doi: 10.1111/ijlh.12526. Epub 2016 Jul 18

 

G. Bastidas, A. Merino. Human African trypanosomiasis diagnosis by peripheral blood smear review in a Spanish traveler. Blood. 2016 Jan 7;127(1):167.

 

A. Merino. Blood film findings in severe babesiosis. Br J Haematol. 2016 Mar;172(6):839. doi: 10.1111/bjh.13845. Epub 2015 Nov 16

 

D.A. Tibaduiza, L.E. Mujica, J. Rodellar, A. Güemes. Structural damage detection using principal component analysis and damage indices. Journal of Intelligent Materials, Systems and Structures, Vol. 27(2), pp. 233-248, 2016, DOI: 10.1177/1045389X14566520.

 

F. Gharibnezhad, L. Mujica, J. Rodellar. Applying robust variant of Principal Component Analysis as a damage detector in the presence of outliers. Mechanical Systems and Signal Processing, Vol. 50-51, pp. 467-479, 2015.

 

L. Bigorra, A. Merino. The unusual presence of Streptococcus gallolyticus within neutrophils in a patient with endocarditis and brain abscesses. Br J Haematol. 2015 May;169(3):308. doi: 10.1111/bjh.13337. Epub 2015 Mar 18

 

S. Alférez, A. Merino, L.E. Mujica, M. Ruiz, L. Bigorra, J. Rodellar. Automatic recognition of atypical lymphoid cells from peripheral blood by digital image analysis. Am J Clin Pathol. 2015 Feb;143(2):168-76; quiz 305. doi: 10.1309/AJCP78IFSTOGZZJN

 

Y. Vidal, C. Tutivén, J. Rodellar, L. Acho. Fault diagnosis and fault tolerant control of wind turbines via a discrete time controller with disturbance compensator. Energies, Vol. 8(5), pp. 4300-4316, 2015.

 

L.E. Mujica, M. Ruiz, F. Pozo, J. Rodellar, A. Güemes. A structural damage detection indicator based on principal component analysis and statistical hypothesis testing. Smart Materials and Structures, Vol. 23 (2), 2013, doi:10.1088/0964-1726/23/2/025014.

 

S. Alférez, A. Merino, L.E. Mujica, M. Ruiz, L. Bigorra, J. Rodellar. Automatic classification of atypical lymphoid B cells using digtial blood image processing. Int J Lab Hematol. 2014 Aug;36(4):472-80. doi: 10.1111/ijlh.12175. Epub 2013 Dec 11

 

M. Anaya, D.A. Tibaduiza, M. Torres, F. Pozo, M. Ruiz, L.E. Mujica, J. Rodellar, C. Fritzen. Data-driven methodology to detect and classify structural changes under temperature variations. Smart Materials and Structures, Vol. 23(4), 2014. doi: 10.1088/0964-1726/23/4/045006.

 

L. Bigorra, S. Alférez, A. Merino, M. Ruiz, L. Mujica, J. Rodellar. Blast cell detection and lineage classification using mathematical morphology and fuzzy clustering on digital blood image analysis. International Journal of Laboratory Hematology, Vol. 35, pp. 100-101, 2013.

 

M. A. Torres-Arredondo, D. Tibaduiza, M. McGugan, H. Toftegaar, K.K. Borum, L.E. Mujica, J. Rodellar, C.P. Fritzen. Multivariate data-driven modelling and pattern recognition for damage detection and identification for acoustic emission and acousto-ultrasonics. Smart Materials and Structures, Vol. 22, 2013. doi:10.1088/0964-1726/22/10/105023.

 

A. Merino. Diagnóstico diferencial de las células linfoides atípicas en sangre periférica. Educación Continuada en el Laboratorio Clínico, Vol.16, pp. 20-40, 2013.

 

A. Merino, J Cid. Very unusual presentation of pernicious anemia with schistocytes in peripheral blood. Blood. 2013 Dec 5;122(24):3862

 

A. Merino, L. Bigorra, J.M. Muñoz. Cytologyc analysis of body fluids for malignancy detection in the emergency laboratory. International Journal of Laboratory Hematology. Vol. 35 pp. 104, 2013.

 

A. Merino, G. Gutiérrez, L. Bigorra, J.C. Reverter. External quality assessment scheme (eqas) for blood smears interpretation: evaluation of the results after two years experience. International Journal of Laboratory Hematology, Vol. 35, pp. 107 – 107, 2013.

 

L. Bigorra, A. Merino, R. García Rosario, M. Serrando. Red cell morphology evaluation applicability using cellavision DM96 digital images. International Journal of Laboratory Hematology, Vol. 35, pp. 102 – 103, 2013.

 

N. Tovar, A. Merino. May-Hegglin anomaly in a patient with HIV infection: Relevance of the peripheral blood film examination. Transfusion. 2013 Jul;53(7):1382

 

S. Alférez, A. Merino, L. Bigorra, M. Ruiz, L. Mujica, J. Rodellar. Atypical lymphoid cells detection and classification on digital blood image analysis, International Journal of Laboratory Hematology, Vol. 35, pp. 100-101, 2013.

 

D.A. Tibaduiza, L.E. Mujica, J. Rodellar. Damage classification in structural health monitoring using principal component analysis and self-organizing maps. Structural Control and Health Monitoring, 2012. Doi: 10.1002/stc.1540.

 

A. Merino. Revisión de la Citología de los Líquidos Biológicos. Educación Continuada en el Laboratorio Clínico, Vol. 15, pp. 42-53, 2012.

 

L.E. Mujica, A. Fernández, A. Güemes, J. Rodellar. Q-statistic and T2-statistic PCA based measures for damage assessment in structures, Structural Health Monitoring, Vol. 10(5), pp. 539-553, 2011.

 

L. Florensa, J.T. Navarro, M.E. Pérez-Vila,…, A. Merino, T. Vallespi, S. Woessner. Linfocitosis B policlonal persistente: estudio de 35 casos. Med Clin (Barc), Vol. 136(13), pp. 565-573, 2011.

 

A. Merino, J.C. Fernández Larrea, J. Bladé. Cytoplasmic inclusions in leukocytes associated to cryoglobulinemia and IgG-kappa monoclonal gammapathy of undetermined significance. Eur J Haematol. 2011 Jun;86(6):550. doi: 10.1111/j.1600-0609.2011.01584.x. Epub 2011 Mar 23

 

A. Merino, R. Brugués, R. García, M. Kinder, F. Torres, G. Escolar.
Estudio comparativo de la morfología de sangre periférica analizada mediante el microscopio y el CellaVision DM96 en enfermedades hematológicas y no hematológicas. Laboratorio Clínico, Vol. 4, pp. 3-14. 2011.

 

A. Merino. Diagnóstico diferencial de las anemias. Educación Continuada en el Laboratorio Clínico, Vol. 14, pp. 45-69, 2011.

 

A. Merino, A. Pereira, P. Castro. Massive intravascular haemolysis during Clostridium perfringens sepsis of hepatic origin. Eur J Haematol. 2010 Mar;84(3):278-9. doi: 10.1111/j.1600-0609.2009.01337.x.

 

M. Díaz, A. Merino, A. Pereira. Erythrophagocytosis in cold agglutinin disease. Transfusion. 2010 Nov;50(11):2310. doi: 10.1111/j.1537-2995.2010.02902.x

 

A. Merino. Signos de alarma en el hemograma y utilidad diagnóstica de la morfología sanguínea. Laboratorio Clínico, Vol. 3(4), pp. 151-152, 2010.

 

A. Merino. Criterios para la realización de la Fórmula Leucocitaria Manual. Educación Continuada en el Laboratorio Clínico, Vol. 13, pp. 49-58, 2010.

 

M. Rigol, N. Solanes, J. Farré, S. Roura, M. Roqué, A. Berruezo, N. Bellera, L. Novensà, D. Tamborero, C. Prat-Vidal, M. A. Huzman, M. Batlle, M. Sitges, J. Ramírez, A. Dantas, A. Merino, G. Sanz, J.Brugada, A. Bayés-Genís, M. Heras. Effects of adipose tissue-derived stem cells therapy alter myocardial infarction: impact of the route of administration. Journal of Cardiac Failure, Vol.16(4), pp. 357-366, 2010.

 

G. Gutiérrez, A. Merino, A. Domingo, J.M. Jou, J.C. Reverter. EQAS for peripheral blood morphology in Spain: six years experience. Int J Lab Hematol. 2008 Dec;30(6):460-6. doi: 10.1111/j.1751-553X.2007.00975.x.

 

J. To, C. Badenas, J.M. Mascaró, I. Madrigal, A. Merino, P. Bastida, M. Lecha, C. Herrero. Study of the genotype-phenotype relationship in four cases of congenital erythropoietic porphyria. Blood Cell Molecular Diseases, Vol. 38, pp. 242-246, 2007.

 

A. Merino, M. Rozman, J. Esteve. Chronic (B-cell) lymhocytic leukemia with unusual granulation. Br J Haematol. 2006 May;133(4):354

 

A. Merino, A. Pereira, M. Zabalza. Erythrophagocytosis in EBV IgM-mediated haemolytic anaemia. Transfusion. 2006 Dec;46(12):2035.

 

A. Merino, J. Esteve. Acute myeloid leukaemia with peculiar blast cell inclusions and pseudo-eosinophilia. Br J Haematol. 2005 Nov;131(3):286

 

A. Merino, J. To, C. Herrero. Atypical red cell inclusions in congenital erythropoietic porphyria. Br J Haematol. 2006 Jan;132(2):124

 

B. Fusté, R. Mazzara, G. Escolar, A. Merino, A. Ordinas, M. Díaz-Ricart. Granulocyte colony-stimulating factor increases expression of adhesion receptors on endothelial cells through activation of p38 MAPK. Haematologica, Vol. 89, pp. 578-585, 2004.

 

A. Merino, R. Mazzara, B. Fusté, M. Díaz-Ricart, M. Rozman, M. Lozano, A. Ordinas. The mesenchymal stem cells revealed. Transfusion. 2003 Jan;43(1):1

 

A. Merino, M. Lozano, P. Marín, R. Mazzara, C. Sanz, A. Ordinas. What does the CD34+ cell look like? Transfusion. 2001 Aug;41(8):975

 

C. Martínez, A. Urbano-Ispizua, P. Marín, A. Merino, M. Rovira, E. Carreras, E. Montserrat. Efficacy and toxicity of a high-dose G-CSF schedule for peripheral blood progenitor cell mobilization in healthy donors. Bone Marrow Transplant, Vol. 24, pp. 1273-1278, 1999.

 

A. Urbano-Ispizua, C. Rozman, C. Martínez, P. Marín, J. Briones, M. Rovira, A. Merino, J. Sierra, R. Mazzara E. Carreras and E. Montserrat. Rapid Engraftment without Significant Graft-Versus-Host Disease After Allogeneic Transplantation of CD34+ Selected Cells From Peripheral Blood. Blood, Vol. 89, pp. 3967-3973, 1997.

 

C. Rozman, A. Urbano-Ispizua, E. Carreras, J. Sierra, P. Marín, M. Rovira, A. Merino, M. Batlle, J. Briones, R. Mazzara and E. Montserrat. Allogeneic Transplants with Peripheral Blood Progenitor Cells: A Report of Six Cases. Leukemia and Lymphoma, Vol. 20, pp. 471-474, 1996.

 

J.L. Vives Corrons, D. Colomer, A. Pujades, A. Rovira, M. Aymerich, A. Merino, J.L. Aguilar. Congenial-6-phosphogluconate dehydrogenase (6PGD) deficiency associated with chronic hemolytic anemia in a Spanish family. American Journal of Hematology, Vol. 53 (4), pp. 221-227, 1996.

Books and chapters
  • Anna Merino.Manual de Citología de Sangre Periférica. Editorial Acción Médica. Madrid, 2005.

 

  • Microorganismos de interés en Citología Hematológica. Club Català de Citologia Hematològica. Editorial Acción Médica. Madrid, 2005.

 

  • Citología de Líquidos Biológicos: Experiencia del Grupo Catalán de Citología Hematológica.Editorial Acción Médica. Madrid, 2011.

 

  • Anna Merino. Manual de Citología de Sangre Periférica y Líquidos Biológicos2ª Edición. Editorial Panamericana. Madrid, 2019.
Patents

Alférez, A. Merino, J. Rodellar, L. Mujica, M. Ruiz. Title: Método implementado por ordenador para reconocimiento y clasificación de células sanguíneas anormales y programas informáticos para llevar a cabo el método. P201331348. Spain. Priority date: May 9, 2013. Owners: Universidad Politécnica de Cataluña and Hospital Clinic de Barcelona.

Doctoral thesis
  • Laura Puigví. Morphological characterization of normal lymphoid cells, reactive, abnormal and blast cells in peripheral blood by means of digital image processing. Supervised by J. Rodellar and A. Merino. 22/10/2019.

 

  • Santiago Alférez. Methodology for automatic classification of atypical lymphoid cells from peripheral blood cell images. Supervised by J. Rodellar and A. Merino. 26/6/2015.

 

  • Gabriela Gutiérrez. Quality external evaluation in peripheral blood cytology: diagnostic competence of the spanish laboratories by means of a new indicator. Supervised by A. Merino. 28/11/2012.